Bovine papillomavirus E1 protein can, by itself, efficiently drive multiple rounds of DNA synthesis in vitro.

نویسندگان

  • C Bonne-Andrea
  • S Santucci
  • P Clertant
چکیده

Bovine papillomavirus E1 protein was found to be as efficient as the simian virus 40 large T antigen in initiating DNA synthesis in a cell-free system derived from COS1 cells. Multiple rounds of DNA synthesis occur, initiated at the bovine papillomavirus type 1 origin. Therefore, E1 functions in vitro as a lytic virus initiator.

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عنوان ژورنال:
  • Journal of virology

دوره 69 5  شماره 

صفحات  -

تاریخ انتشار 1995